![]() ![]() Diet (grapefruit juice and several drugs, green vegetables, and warfarin).The factors that affect the half-life include: The half-life of the drug is useful in determining the dosing frequency. The half-life is the time required for half of the drug to be metabolized and eliminated from the body. The half-life of the drug is useful in determining the dosing frequency.ĭrug Half-life (t1/2) is defined as the amount of time required for the drug concentration to be reduced to exactly half its initial concentration or amount in the blood.
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